• Extremely potent analog of capsaicin, the major active principle of common red pepper. Szallasi, A. and Blumberg, P.M. "Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper." Neuroscience 30: 515-520 (1989).
• STABILITY AND STORAGE: Resiniferatoxin (RTX) is susceptible to slow degradation if exposed to air. Even at -20 ºC, RTX will develop a few tenths of a percent of impurities over a period of several months if air is not rigorously excluded. Thus, RTX must be stored in an inert atmosphere for long-term stability. All of our catalog sizes (1, 5, 10, and 25 mg) are flame-sealed under nitrogen or argon in Type I Borosilicate glass ampules. Under these conditions RTX is stable for many years. Once removed from the original ampule, for best long-term storage it is recommended that RTX be stored at -20 ºC or colder in a very tightly sealed container with an inert atmosphere such as nitrogen or argon. Note that a screw-cap container would require a melted wax seal to prevent slow loss of the inert gas and entry of air. Very few types of container closures other than flame-sealed glass are truly airtight.
• CAUTION: RTX in powdered form is extremely irritant to the eyes, mucous membranes and lungs. Handling RTX in powdered form should be avoided if at all possible. If the powdered form must be handled, full face, respiratory and body protection should be worn.
• Please request Technical Note #28 for additional information.
• Pharmaceutical formulations containing this compound, and anti-inflammatory, anti-viral and anti-psoriatic uses, are covered by U.S. patents 5,643,948 and 5,955,501.
• Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.

Related Terms: